2015/10/28 菊池

明日の私の発表は、論文紹介は省略し、データについてお話したいと思います。

神経科学学会発表と重なりますが、いくつか載せることのできなかったデータやその後集めた文献などについてお話したいと思いますので、よろしくお願いいたします。

2015/10/14 鮫島

Signatures of Value Comparison in Ventral Striatum Neurons

Caleb E. Strait, Brianna J. Sleezer, Benjamin Y. Hayden
PLoS Biol. 2015 Jun; 13(6): e1002173.

明日は、ちょっと古いですけどHaydenのPlos biologyの論文を中心に、 「価値に基づく意思決定がどこでどのようにおきるか？」について、 またそれを検証する方法について考えたいと思います。

 よろしくお願いします。

Abstract
The ventral striatum (VS), like its cortical afferents, is closely associated with processing of rewards, but the relative contributions of striatal and cortical reward systems remains unclear. Most theories posit distinct roles for these structures, despite their similarities. We compared responses of VS neurons to those of ventromedial prefrontal cortex (vmPFC) Area 14 neurons, recorded in a risky choice task. Five major response patterns observed in vmPFC were also observed in VS: (1) offer value encoding, (2) value difference encoding, (3) preferential encoding of chosen relative to unchosen value, (4) a correlation between residual variance in responses and choices, and (5) prominent encoding of outcomes. We did observe some differences as well; in particular, preferential encoding of the chosen option was stronger and started earlier in VS than in vmPFC. Nonetheless, the close match between vmPFC and VS suggests that cortex and its striatal targets make overlapping contributions to economic choice.

じっさいの実験データも公開されています。

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